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KMID : 0984720060380060398
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Infection and Chemotherapy
2006 Volume.38 No. 6 p.398 ~ p.402
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A Case of Cytomegalovirus Enterocolitis and Jejunal Perforation During Immune Reconstitution with Highly Active Antiretroviral Treatment
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Choi Se-Ho
Kang Hyo-Sung
Lee Sung-Ho
Lee Jong-Hyun
Seon Kyoung-Youn
Nam Seung-Woo
Hwang Jae-Kwan
Shin Hyoung-Shik
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Abstract
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Immune reconstitution syndrome (IRS) in HIV-infected patients is an adverse consequence of the restoration of pathogen-specific immune responses during the initial months of highly active antiretroviral treatment(HAART). Previously subclinical infections are unmasked or pre-existing opportunistic infections clinically deteriorate as host immunopathological inflammatory responses are switched on. While the eye is the area where Cytomegalovirus(CMV)-associated IRS occurs most often in patients with AIDS, it also can present with intestinal or pulmonary involvement. We present a case report of an HIV-infected patient in whom CMV enterocolitis and jejunal perforation developed after HAART.
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KEYWORD
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Cytomegalovirus, Enterocolitis, Immune Reconstitution syndrome, Highly Active Antiretroviral therapy
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